Specific cells of the Immunity appear stack at the time of puberty in the testes. What prevent the body from rejecting the sperm just created.
We knew that the testes contained specific cells of the immunity, the macrophages. But the team of Michael Sieweke (Center of Immunology Marseille Luminy) just to discover that the two types of macrophages existing testicular have a location and a different origin, adapted to their functions.
The macrophages located in the vicinity of testosterone-producing cells have a embryonic origin. While those who are located around the seminiferous tubules (place of production of the sperm) originate from the bone marrow, and appear in the testes of mice 2 weeks after the birth, at the time where the sperm begins to be product (the equivalent of puberty in humans).
Thwart the immune system attack
the sperm appearing in the body after the establishment of the immune system, the latter could be regarded as exogenous and attack it. The role of macrophages could be to counteract this attack.
by : 05 sept 2017 .
We knew that the testes contained specific cells of the immunity, the macrophages. But the team of Michael Sieweke (Center of Immunology Marseille Luminy) just to discover that the two types of macrophages existing testicular have a location and a different origin, adapted to their functions.
The macrophages located in the vicinity of testosterone-producing cells have a embryonic origin. While those who are located around the seminiferous tubules (place of production of the sperm) originate from the bone marrow, and appear in the testes of mice 2 weeks after the birth, at the time where the sperm begins to be product (the equivalent of puberty in humans).
Thwart the immune system attack
the sperm appearing in the body after the establishment of the immune system, the latter could be regarded as exogenous and attack it. The role of macrophages could be to counteract this attack.
by : 05 sept 2017 .
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